Human Growth Hormone (somatropin also referred to as rHGH, hGH, or GH) is created by the pituitary gland, the primary form consisting of a 191 amino acid chain. When we are young, HGH is in large part responsible for the proper growth of our bones, muscles and other tissues; not enough of this hormone and we don't grow and remain dwarfs… however too much of this hormone and we become giants or suffer from an abnormal growth deformity. As we grow into adulthood, hGH is responsible for keeping our muscles from wasting away, supports our healthy immune system responses and regulates aspects of our metabolic functions, dealing with increased fat metabolism and healthy body composition later in life; in additon hGH maintains and repairs our skin and other tissues.
Levels of hGH in our bodies usually peak while we are in adolocence, then begin to taper off during our early 30s; thus by the time we reach or 60s our levels of hGH secretion being produced daily is as low as 10% of what it was during our youth; thus producing the age markers showing decreased hGH levels listed below:
· Increase in fat · Decrease in muscle and lean body structures · Decreased skin texture resulting in a less youthful appearance · Decreased bone density, onset of osteoporosis · Decreased brain function, loss of intellect with aging · Decreased sex drive · Decrease in overall physical and mental well being · Increase in sleep disorders, lower quality of sleep · Depression and fatigue.
HGH Therapy can reverse or improve these symptoms in the majority of patients that engage in this therapy. This is why you will often hear references with respect to HGH, as “The Fountain of Youth” and other similar terms. It can present a better quality of life for those aging, as well as provide many other great benefits.
HGH (and IGF-1 which is a result of its use) is the only substance that can actually initiate hyperplasia, which equates to new muscle cells. While use of anabolic steroids can cause hypertrophy (the enlargement of existing muscle cells), steroids do not offer the ability to recruit and mature more muscle cells; HGH can. HGH also increases protein synthesis, which can be responsible for hypertrophy. HGH also strengthens and heals connective tissues, cartilage, and tendons. These uses are what make it so attractive to athletes in all sports.
Human growth hormone (HGH - somatropin/somatotropin) is one of the most abundant hormones secreted by the anterior lobe of the pituitary gland or otherwise known as the Hypophysis. Once gh or growth hormone is released by the pituitary gland it is quickly taken in by the liver and converted into growth factors, the most important growth factor is the one called IGF-1.
These growth factors are the messengers that carry the signals or messages to the cells of the body. This communication regulates the growth of cells, telling them when to live and when to die. Cellular reproduction slows, unless the cells are prompted by the growth factors of hGH and IFG-1. During the growth and development stage of life, human growth hormone is responsible for proper growth and development of our muscles and bones. However once adulthood is reached hGH slows production which causes our bodies to change as we age, increase in belly fat, sagging skin, increased immune disorders, and that is what we strive to curver; the process of our bodies aging as we grow older. The importance of hGH is that it effects almost every cell of our body and helps to keep the cells and systems healthy.
Healthy levels of hGH account for things such as good muscle/fat ratio, a high libido, good sexual function, energy and endurance, good muscle tone, menopause, improved sleep, increased bone-density, regulates our blood pressure and better overall skin. As we age the function of the pituitary gland releases lower and lower amounts of HGH into the bloodstream for the body to use. Therefore we inject bio-synthetic somatropin which is an exact replica of what our bodies produce, back into the endocrine system to slow and reverse these aging symptoms.
HOW DOES hGH WORK SYSTEMICALLY?
HGH is short lived, but during its short half-hour activity per burst from the pituitary gland; it exerts itself through direct and indirect effects. Its direct effects are the result of the HGH binding its receptor on target cells (as the chart above). Fat cells (adipocytes) as well as myocytes (muscle cells) have HGH receptors. On fat cells, HGH stimulates them to break down triglyceride and suppresses the fat cells ability to uptake circulating lipids.
Its indirect effects are in the process we described in the section above. When HGH travels to the liver, the result in its pass through the liver is the secretion of IGF-1. When this IGF-1 is secreted, it stimulates proliferation of chondrocytes (cartilage cells), which result in bone growth. It also plays a part in stimulating both the proliferation and differentiation of myoblasts (the precursor to skeletal muscle fibers). IGF-1 also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
HGH stimulates protein anabolism in many tissues. This reflects increased protein synthesis, decreased oxidation of proteins, and increased amino acid uptake. As mentioned above, HGH enhances fat utilization by stimulating triglyceride breakdown and oxidation in fat cells (adipocytes).
HGH can affect the function of other hormones. HGH can suppress the abilities of insulin to stimulate the uptake of glucose in tissues and enhance glucose synthesis in the liver, though administering hGH actually stimulates insulin secretion and can create a state of hyperinsulinemia. This combination can lead to decreased insulin sensitivity, which in turn can lead to hyperglycemia. HGH can also have a slight inhibitory effect on the thyroid, though this varies greatly from individual to individual.
Therefore we have a hormone that can assist with maintenance and the healing of most of our body's systems, it can create new cartilage, increase bone density, increase muscle cells, assist with protein uptake, decrease oxidation of proteins, and can accelerate the rate at which fat in our bodies is utilized. This is why excitement follows HGH and it's related therapies. You may ask, How do I utilize this hormone to my advantage? Look at our exogenous HGH therapy by going to the "Get Started" link and signing up for our HRT therapy; you'll be glad you took this fist step to a whole new you.
* Human Growth Hormone (hGH) is only available in injectable form. hGH is not available in tablet, capsule, cream or spray form. hGH can only be applied via syringe injected sub-cutaneously.
